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GLUPRIDE  Multi

Glupride Multi  is a unique vitamin/herbal formula designed to promote health of people with Diabetes, Pre-Diabetes and Metabolic Syndrome X.

Glupride Multi was created by Sarfraz Zaidi, MD, a respected Endocrinologist, an expert in the field of Diabetes and author of the book, Take Charge Of Your Diabetes". Dr. Zaidi, is a physician certified by the American Board of Internal Medicine. He is the medical director of the Jamila Diabetes & Endocrine Medical Center in Thousand Oaks, California. He is a leading authority in the field of diabetes and Insulin Resistance Syndrome. He frequently lectures other physicians and has written an instructional CD-ROM for physicians.

Dr. Zaidi reviews scientific studies regarding the role of vitamins and herbs in the treatment of diabetes. Vitamins and minerals are essential for the normal metabolism of our body.

Endocrinologists are expert in the field of metabolism. Unfortunately, non-physicians have jumped into this field to take advantage of a good  business opportunity. Often, the public is misled by sale pitches, which have no scientific basis and sometimes may even be harmful.

For example, most multivitamins contain Potassium, Vitamin K, Vitamin E and Iron. Most diabetic patients are on an Ace-inhibitor drug (such as Altace, Vasotec, Accupril, Zestril, etc) or an ARB drug (such as Cozaar, Avapro, Atacand, Benicar Diovan, etc). These drugs can increase the potassium level in blood, which can be life-threatening.

Potassium in a multi-vitamin can further increase this potassium level. Patients usually do not tell their physicians they are taking vitamins that contain potassium. When a physician encounters a patient with a high potassium level, they often stop the Ace-inhibitor or ARB drug, inadvertently depriving the patient of the beneficial effects of these  wonderful drugs.

Most diabetics have underlying insulin resistance, which increases the level of many clotting factors, therefore increasing risk for clot formation and acute vascular events, such as a heart attack and stroke.  An extra dose of Vitamin K in multivitamin preparations may actually be harmful in these patients. It's like adding fuel to the fire.

Also, many of these patients are on Coumadin. Vitamin K interferes with Coumadin and it becomes extremely difficult to find the right dose of Coumadin in these patients.

Most recent studies show that Vitamin E in large doses may not be cardio-protective and may even be harmful. However, most multi-vitamins continue to include mega doses of Vitamin E.

Iron interferes with the absorption of thyroid hormone.

GLUPRIDE Multi

Glupride-Multi does not contain Potassium, Vitamin K or Iron.

It contains small amounts of Vitamin E to meet the daily requirements.

Glupride Multi contains 21 different vitamins, minerals and herbs.

It contains Alpha-Lipoic Acid,  Chromium Picolinate, Cinnamon and Coenzyme Q 10 in

addition to B vitamins, Vitamin A, Vitamin E, Vitamin C and essential minerals

including Selenium, Zinc, Vanadium and Magnesium. 

Alpha-Lipoic Acid

Alpha-lipoic acid is normally produced in cells in small amounts and helps in the normal metabolism of glucose. Alpha-lipoic acid functions as a strong anti-oxidant in the body (1, 2).

The cells of diabetic patients are under a tremendous amount of daily oxidative stress. That's why it makes sense to use Alpha-Lipoic acid as a dietary supplement in people with diabetes.

A number of scientific studies have shown that alpha-lipoic acid promotes normal insulin sensitivity and thus may promote health in diabetic patients (2).

Several studies have also shown alpha-lipoic acid to be helpful in promoting nerve health in humans (3).

In Germany, Alpha-lipoic acid has been used for over 30 years.

Chromium picolinate

Chromium picolinate is required for the normal metabolism of glucose. Several studies have shown beneficial effects of chromium supplementation in promoting health of diabetic patients.

One large clinical trial tested chromium picolinate in 833 Type 2 diabetic patients and found a significant improvement in their blood glucose values (4).

Cinnamon

Physicians have long been intrigued by the beneficial effects of cinnamon on the health of people with diabetes.

In December 2003,  an excellent scientific study was published in Diabetes Care, (5) in which cinnamon powder was used in 60 patients with Type 2 diabetes. Three daily doses, 1 gram, 3 grams and 6 grams were used.

There was a decrease in blood glucose by 18-29%. Serum triglycerides also decreased by 23-30%.

Patients consuming 6 grams of cinnamon powder per day appeared to have achieved results earlier (at 20 days), but at 40 days, all doses had the same efficacy in lowering blood glucose and triglycerides level.

Coenzyme Q10

Coenzyme Q10 is a strong antioxidant. It may help to improve diastolic dysfunction of the heart in patients with hypertension, which is so commonly present in patients with diabetes.

Statin drugs such as Lipitor, Zocor, Pravachol and Crestor are commonly used in diabetic patients. Unfortunately, these drugs not only reduce cholesterol level, but also may reduce CoQ10  level as was demonstrated in a recent study from investigators at Columbia University (6). This phenomenon may explain the muscle aches these patients often experience while on a statin drug.

Selenium, Zinc and Magnesium have all been shown to be beneficial for people with diabetes.

GLUPRIDE Multi

 Supplement Facts 

Serving Size: 2 Tablets    Servings per container: 30

Amount Per Serving                        % Daily Value

Vitamin A               5000 I.U.                 100%

Vitamin C               100 mg                    183%

Vitamin E               20 I.U.                     66%

Thiamin                  2 mg                       133%  

Riboflavin               2 mg                        118%

Niacin                    50 mg                      250%

Vitamin B6              10 mg                      500%

Folic acid                800 mcg                   200%

Vitamin B12            960mcg                    16000%

Biotin                     200 mcg                   67%        

Pantothenic acid      10 mg                      100%

Magnesium Oxide     100 mg                    25%       

Iodine                     150 mcg                  100%                

Zinc                        20 mg                     133%

Selenium                  100 mcg                 143%

Manganese               4 mg                      200%

Chromium                 800 mcg                 667%

(as Chromium picolinate)

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*Alpha Lipoic Acid               600 mg

*Coenzyme Q 10                 20 mg

*Cinnamon bark powder       200 mg 

*Vanadium                         10 mcg      

*Daily Value not established.